

Leuphasyl
Pentapeptide-18 Enkephalin Analog
Leuphasyl (Pentapeptide-18) is a synthetic enkephalin analog developed for cosmetic formulation research. It has been studied in preclinical models as a topical synergist to Argireline, with mechanism work examining its effect on presynaptic muscle contraction signaling pathways distinct from the SNARE-targeting class. For laboratory research use only.
Agonizes enkephalin-class opioid receptors on motor neurons, reducing cAMP and limiting calcium influx, which attenuates acetylcholine release at the neuromuscular junction.
For Research Use Only. Sold for in vitro laboratory research. Not for human or veterinary consumption. By purchasing, you confirm you are 21+ and a qualified research professional.
Pentapeptide-18 — synthetic enkephalin analog (Tyr-Gly-Gly-Phe-Leu).
Every batch of Leuphasyl ships with an independently conducted Certificate of Analysis by Janoshik Analytical or Bioviridian. The COA includes HPLC-MS chromatogram, mass spec confirmation, endotoxin levels, and heavy metals screening.
Batch number is printed on the vial label and included in your order confirmation email. Look it up at pepidyn.com/coa.







