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FOXO4-DRI — Senolytic D-Retro-Inverso Peptide
FOXO4-DRI — Senolytic D-Retro-Inverso Peptide
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Longevity

FOXO4-DRI

Senolytic D-Retro-Inverso Peptide

Price
$135.00
Dosage
10 mg
Format
vial
COA on this batch
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About

FOXO4-DRI (FOXO4-p53 interfering peptide) is a D-retro-inverso peptide engineered from the FOXO4 sequence to disrupt the FOXO4-p53 interaction. Subject of preclinical aging research as a senolytic agent that selectively induces apoptosis in senescent cells while sparing healthy proliferating cells. For laboratory research use only.

Mechanism

Competitively disrupts the FOXO4-p53 interaction within senescent cells, releasing nuclear p53 to trigger intrinsic apoptosis selectively in cells with elevated FOXO4 expression.

For Research Use Only. Sold for in vitro laboratory research. Not for human or veterinary consumption. By purchasing, you confirm you are 21+ and a qualified research professional.

Molecular structure
Sequence
(D)LTLRKEPASEIAQSILEAYSQNGWANRRSGGKRPPPRRRQRRKKRG
HydrophobicPolarBasic (+)Acidic (−)Aromatic

D-Retro-Inverso peptide from FOXO4 transactivation domain; disrupts FOXO4-p53.

Molecular weight
5,260 g/mol
FOXO4-DRIDrag · Scroll to zoom
Specifications
Product
FOXO4-DRI
Subtitle
Senolytic D-Retro-Inverso Peptide
Dosage
10 mg
Form
Vial
Category
Longevity & Mitochondrial
Sku
foxo4-dri-10mg
Purity target
≥99% (HPLC-MS)
Storage
2-8°C lyophilized
Shelf life
24+ months refrigerated
Verification

Every batch of FOXO4-DRI ships with an independently conducted Certificate of Analysis by Janoshik Analytical or Bioviridian. The COA includes HPLC-MS chromatogram, mass spec confirmation, endotoxin levels, and heavy metals screening.

COA available per batch

Batch number is printed on the vial label and included in your order confirmation email. Look it up at pepidyn.com/coa.